Two years ago Giorgio had colon cancer and received surgical treatment and chemotherapy. He also suffers from hypertension and one year ago he had a stroke which has left him unable to walk. Giorgio has skin phototype I and his father died of melanoma. He has monthly checkups with his GP; during the last checkup the GP noticed the transformation of a mole. Considering his family history and personal risk factors the GP started care and support planning. The GP sent an image of the mole to a specialist dermatologist through a teledermoscopy platform. During teleconsultation via the teledermoscopy platform patients are triaged according to dermatoscopic features of the lesions evaluated. Giorgio’s lesion was classified as “severe graded atypia” and surgical immediate removal was planned. Histological examination confirmed a melanoma diagnosis.